An Important Chapter in the Infection–Malnutrition Story

Indi Trehan, Mark J Manary

In this issue of The Lancet Global Health, Jay Berkley and colleagues in Kenya present the results of their outstanding clinical trial of antibiotic prophylaxis for children who recovered from complicated severe acute malnutrition (SAM). The high rates of mortality and nutritional relapse observed among children who recover from SAM have also been seen in children recovering from moderate acute malnutrition. These children may require a higher anthropometric threshold for recovery, which may serve as a marker of improved immune status and decreased susceptibility to infection.

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