van Bovenemail M, van Lier A
Universal vaccination programmes have greatly reduced the burden of infectious diseases in both developing and developed countries. In the 1960s and 1970s, these reductions led to optimism that a victory in the battle against infectious diseases could be within reach. Unfortunately, even though the benefits of most childhood vaccinations are scientifically unquestioned, vaccination coverage rates are far from 100% in many countries, and show substantial variation. Early detection of trends and an improved understanding of underlying mechanisms are paramount to be able to improve vaccination policies.